Description du produit

This extensively up-dated and expanded edition provides the busy clinician with an essential overview of the latest developments in human cancer genetics - an area that has made significant advances since publication of the first edition. The opening section presents the principles of cancer genetics and introduces the basic concepts and mechanisms of tumorigenesis and inherited predisposition to cancer. The second part of the book provides information, on a systems basis, on the incidence, significance and management of predisposition to individual cancers. The final section then deals with specific inherited cancer syndromes, giving practical guidance on clinical investigation, screening and management of affected patients and relatives at risk. Up-to-date details of the genetic mapping of inherited cancer syndromes and the molecular genetic changes in individual cancers are also provided. Finally, an appendix provides a helpful revision guide to the fundamental principles of genetics. This practical and clear account will benefit clinicians and research workers in oncology, genetics, surgery and general medicine.

Détails sur le produit

• Publié le: 1994-01-27
• Langue d'origine: Anglais
• Reliure: Relié
• 258 pages

JA Majors Book Info
Guy's & St. Thomas's Hospitals, UK. Provides an overview of the latest developments in human cancer genetics. Covers the principles of cancer genetics, the predisposition to individual cancers specific inherited cancer syndromes, and a guide to the principles of genetics. This edition has been significantly revised. Previous edition: c1993. For practitioners. Softcover.